Compatibility answer

Will the MX500 500GB SATA M.2 (CT500MX500SSD4) work with the ASUS ROG STRIX B550-F GAMING (WI-FI)?

Q: Will the MX500 500GB SATA M.2 (CT500MX500SSD4) work with the ASUS ROG STRIX B550-F GAMING (WI-FI)?

Yes. Direct fit. Sources: https://rog.asus.com/motherboards/rog-strix/rog-strix-b550-f-gaming-wi-fi-model/spec/, https://www.crucial.com/ssd/mx500/ct500mx500ssd4

Yes. Direct fit.

Both records are reviewed against the manufacturers' sources; sources last checked 2026-10-14. Informational only: confirm with the manufacturer before buying.

Why

✓ 2280 fits the M.2 2242/2260/2280/22110 bay.
✓ SATA is supported by this slot.

Sources

ASUS ROG STRIX B550-F GAMING (WI-FI): specs from ASUS ROG specifications, checked against the source 2026-10-13.
MX500 500GB SATA M.2 (CT500MX500SSD4): specs from Crucial: MX500 500GB M.2 2280 (CT500MX500SSD4), checked against the source 2026-10-14.

Check your exact setup

Other parts in the cart, current configuration (installed memory, fan brackets) and adapters can change the answer.

Check a whole cart

Also checked with the ASUS ROG STRIX B550-F GAMING (WI-FI)

16GB DDR4-3200 desktop DIMM (CT16G4DFRA32A) Yes
970 EVO Plus 1TB NVMe M.2 (MZ-V7S1T0) Yes
990 PRO 1TB NVMe M.2 (MZ-V9P1T0) Yes
AMD Ryzen 5 5600X Yes
AMD Ryzen 7 5800X Yes
AMD Ryzen 7 5800X3D Yes
AMD Ryzen 9 5900X Yes
AMD Ryzen 9 5950X Yes

Everything checked with it

AI assistants and developers: the same answer, with a signed receipt, from check_compatibility at https://tetheredtrust.com/mcp or POST https://tetheredtrust.com/v1/check with existing_id: "asus-rog-strix-b550-f-gaming-wifi", candidate_id: "crucial-mx500-m2-500gb".